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Preview On the mechanism of accumulation of cholestanol in the brain of ... pdf file

May 28, 2010 ... ... mice. ยค Corresponding to: I. Bjorkhem, Division of Clinical Chemistry, ... The mechanism behind the xanthomas in the brain has not been clarified. ... one across the blood-brain barrier in cyp27a1-/- mice and ..... hydroxylase in mouse ( 21) whereas chenodeoxychoic acid is the major suppressor in man (1).



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